RTK is in use at universities, corporations, and research institutions throughout the world. Follow these links to find out how RTK has been used in diverse application areas.

iMagX: iMagX is a public-private partnership between the UCLouvain and IBA, world leader in proton therapy. The team designs and implements complete imaging solutions. Two of these solutions, a registration software and a cone beam computed tomography (CBCT) system, are both based on RTK and are distributed by IBA in adaPT insight, their certified software suite for patient alignment in proton therapy.
radART institute: The radART institute (Paracelsus Medical University, Salzburg) and medPhoton GmbH (Salzburg) use RTK as a basis for their inline cone-beam computed tomography reconstruction module, namely ORA-CBCT. ORA-CBCT is intending to support reconstruction from non-isocentric acquisitions besides standard C-arm trajectories with special focus set on the Patient Alignment Imaging Ring (PAIR) system's geometrical characteristics. Non-isocentric acquisition trajectories provide new opportunities such as particularly large field of view and limited region of interest reconstructions. Deduced findings and optimizations regarding the reconstruction algorithms and related pre-processing are back-contributed to RTK. Moreover, the joint Dual-Energy X-ray imaging for TargEting Radiotherapy (DEXTER) project between radART and CREATIS involves ORA-CBCT for real-world acquisition and experiments.
Rotaplus: Rotaplus is a registration software developped by Institut Curie to set patients to their treatment positions for protontherapy irradiation. It has ability to compute 6 degrees of freedom correction vectors to go from current real patient position to final planed position. This correction vector can be obtain whether using fiducial markers registration or manual anatomical matching between real radiographs and planed Digitally Reconstructed Radiographs (DRR). The DRR computation is now powered by RTK and used in clinical routine for correction and validation of every positioning in one of Institut Curie protontherapy treatment rooms.